Microwave adverse exposure changes of blood and brain levels of some elements in rats

In this work, four groups of adult male albino rats were used; the first as control, the second was exposed to microwave radiation 11/2 hr/day for seven consecutive days at a dose of 15 mW/cm2 and frequency 10.525 CHz. The third was exposed like the second but for 24 consecutive days, while the fourth was treated as the third and then left for two weeks as a rest period. Then animals were sacrificed and the blood and brain levels of some major and trace elements [calcium. iron, manganese, copper, nickel, zinc, selenium and molybdenum] were estimated by the Energy Dispersive X-ray Fluorescence technique [EDXF]; an easy, rapid, multi-elemental and need low weight of samples. Calcium, iron and manganese showed a significant increase in the exposed groups, while zinc, copper and molybdenum showed a significant decrease in both blood and brain when compared to control. Nickel of blood exposed groups showed a significant drop in the acute and chronic exposure groups and restored its normal figure in the chronic exposure then rest group, but it gave no readings in the brain sample for all groups. As for selenium it showed a significant drop in both acute and chronic exposure groups and a significant rise in the chronic then rest group in the blood; but in brain it gave no readings for the control and chronic exposure groups and a significant rise in the other two. These changes were explained by the microwave variant effects on ion fluxes via the effect on the ion channel properties of cell membrane, interaction between the cellular membrane molecules containing these ions, voltage changes across the cell membrane. etc

study of the possible hazards of acute and chronic exposure to microwaves on hepatorenal function and some blood trace elements in albino rats

Microwave exposure possess some degree of health hazards, the objective of the present study was the investigation of the possible effects of acute and chronic exposure to radiation on some liver, kidney, tissue antioxidants enzymes as superoxide dismutase, glutathione peroxidases, glutathione and toxic free radical lipid peroxide that results from stress oxidative tissues damage as well as the effect of microwaves on some trace elements that acts as metalloenzyme as zinc, selenium, copper and manganese. The result of the present study showed that exposure to microwaves [acute and chronic] produced significant reduction of antioxidant enzymes as superoxide dismutase, glutathione peroxidase and glutathione content. It also produced significant increase in toxic free radical malondialdehyde. These changes are more manifested with acute exposure [7 days]. The parameters of this study were improved with concomitant administration of DDB [well known antioxidant and tissue protective]. Also, the results showed that there was significant impairment of liver and kidney parameters with acute exposure and still there were changes in chronic which were insignificant. The parameters of liver and kidney were improved by the administration of DDB concomitantly

Evaluation of the possible effects of microwaves on some vasoactive substances serotonin [Part I] and some metabolite [part II] steptozotocin induced diabetic rats

The objective of this study was the evaluation of the possible adverse effects of microwaves [e.g. mobile, microwave ovens, etc.] on some vasoactive substances as catecholamine [norepinephrine and epinephrine], 5 hydroxy tryptamine [serotonin] and histamine as well as histaminase enzyme activity and the possible role of Nigella sativa oil [NSO] administration in albino rats. Male adult albino rats were divided into control group [n=10], group II [n=10] received microwaves for 7 days consecutively at a dose of 170 mW/Cm2 and frequency of 2.06 GHz for 3 hours [acute group], the third group [group III] [n=10] received the same dose as group II but for 28 consecutive days [chronic group], the fourth group [group IV] was treated as group II with concomitant administration of Nigella sativa oil [NSO] 100 mg/kg/day/orally by gastric tube. The fifth group [n=10] was treated as group III with concomitant oral administration of Nigella sativa oil in the same dose as group IV for 28 days. At the end of experiments, the animals were sacrificed and blood examined for norepinephrine, epinephrine, serotonin, histamine and histaminase enzyme activity. The result of the present study showed that microwaves produced significant reduction of histaminase activity significant increase in histamine, serotonin, norepinephrine and epinephrine, all were highly significantly changed in acute group of irradiation